The address for the center is 6100 Colwell Blvd., Suite 100, Irving, TX 75039-3112.

From downtown Dallas on TX-114 Westbound:
• Take Exit "TX-348 Spur/Northwest Hwy/Hidden Ridge Dr"
• Move into the far-right lane. At the stop light, continue straight. Colwell Blvd. begins.
• Go 1 mile and the Presbyterian Mission Center is on the right.

From TX-114 Eastbound:
• Exit "Walnut Hill Ln/Hidden Ridge Dr"
• On the frontage road, stay in the far-left lane and continue to the stop light (Hidden Ridge Dr.) Turn left.
• Stay in the far-left lane, at the next stop light, turn left. Colwell Blvd. Begins.
• Go 1 mile and the Presbyterian Mission Center is on the right.

From the east on I-635 Westbound:
• Take Exit 29 to Valley View Ln.
• Turn left at Valley View Ln.
• Turn left at Riverside Dr. Go 1.4 miles. Go through the light at Royal Lane.
• Turn right at Creative Way.
• Turn right at Colwell Blvd. Presbyterian Mission Center is on the right.

From the west on I-635 Eastbound:
• Exit MacArthur Blvd.
• Take a right at MacArthur Blvd.
• Get in the far-left lane, take a left at Royal Lane
• Turn right at Colwell Blvd.
• The Presbyterian Mission Center is on the left.

From the south on TX-161 N/Bush Turnpike:
• Take exit to Royal Ln (TX-114).
• Continue on frontage road across TX-114.
• Take the Royal Ln. ramp.
• Turn right at Royal Ln. (East)
• Follow Royal Ln. across MacArthur Blvd to Colwell Blvd.
• Bear right at Colwell Blvd. Presbyterian Mission Center will be on your left.

From the north on Bush Turnpike:
• Take Exit "635/Las Colinas Blvd".
• Follow Las Colinas Blvd Exit.
• Left at traffic light, over highway, south on Las Colinas.
• Left at Royal Lane.
• Right at Colwell Blvd. Presbyterian Mission Center is on the left.